The only incompatibility issues would come from the programs you are using to write in, ie. what kinds of files the wordprocessors on the different computers have. There shouldn't be any compatibility issues for using the dive in computers that use different OS's. They are just plug and play things :) It is like opening a burned cd, or saving it to a disc, or anything else like that, only tiny, portable, a zillion times more space, and ease of transfer, etc :D They really are great. All you need is a usb port :D

I'm a giant dork and have mirc saved on mine, so that I can use it from anywhere ;) Well, any computer that has a platform mIRC will run from, I suppose :o